Macam Dosis Dari Obat Antiemetik Lengkap
Macam Dosis Dari Obat Antiemetik Lengkap - Salam farmasi indonesia, sesuai dengan judul kali ini saya akan membagikan sebuah artikel mengenai macam macam dosis dari obat antiemetik, yang merupakan salah satu tugas dari mata kuliah pengantar ilmu farmasi, berikut langsung saja penjelasannya.
DAFTAR PUSTAKA
1. Centers for Disease Control and Prevention. December 12, 2011. Put your medicines up and away and out of sight -
2. The Center for Improving Medication Management and the National Council on Patient Information and Education. The quick scoop: medicines and your family: safely storing and disposing of medicines - Diakses: June 10, 2016.
3. U.S. Food and Drug Administration. December 24, 2013. How to dispose of unused medications –
4. World Health Organization: Information sheet: Pharmaceuticals in drinking-water –
5. Lyon, R. C., Taylor, J. S., Porter, D. A., et al. (2006)
Stability profiles of drug products extended beyond labeled expiration dates. Journal of Pharmaceutical Sciences; 95:1549-60 -
6. Harvard Medical School (2016). Drug Expiration Dates - Do They Mean Anything? –
http://de.drogen.wikia.com/wiki/LSD http://dechacare.com/OMEPRAZOLE-P561-1.html http://milissehat.web.id/?p=1215 http://nslijlab.testcatalog.org/show/PROMETH http://pionas.pom.go.id/monografi/ondansetron http://reference.medscape.com/drug/antivert-bonine-meclizine-343062 http://wildhealthh.com/id/pages/1349499
http://www.drugbank.ca http://www.drugbank.ca/drugs/DB00186 http://www.drugbank.ca/drugs/DB00321 http://www.drugbank.ca/drugs/DB00404 http://www.drugbank.ca/drugs/DB00975 http://www.drugbank.ca/drugs/DB01069
http://www.mipa-farmasi.com/2016/06/klorpromazin.html
https://aciibook.com/toxbook/trimetobenzamid-antiemetik/ https://bukusakudokter.org/2013/03/28/chlorpromazine/ https://pubchem.ncbi.nlm.nih.gov/compound/clebopride_malate https://www.drugs.com/dosage/compazine.html https://www.drugs.com/dosage/trimethobenzamide.html https://www.drugs.com/pro/metoclopramide-tablets.html https://www.farmasi-id.com
https://www.healthcare.uiowa.edu/path_handbook/handbook/test928.html www.mayomedicallaboratories.com
Macam Dosis Dari Obat Antiemetik
NO | Nama Obat | Dosis
Lazim |
Dosis
Maksimum |
Dosis
Toksik |
Dosis Letal | Indeks
Terapi |
1. | Metoclopramide | 3x sehari
10mg |
30 mg
perhari |
30-40
mg/hari |
Oral, tikus LD 50 :
280 mg / kg |
- |
2. | Clebopride maleate | 3x sehari
10-20 mg |
60 mg
perhari |
- | - | - |
3. | Promethazine | sehari 25-
75 mg |
100 mg
perhari |
1 gram /hari | LD50 = 55mg / kg
(IV pada mencit) |
20 ng/ml
<150 ng/ml |
4. | Domperidone | 3xsehari | 80 mg | - | - | 10- |
10-20 mg | sehari | 70ng/ml | ||||
5. | Ondansetron | Oral : 8 mg | - | - | - | 10-500
ng/ml |
6. | Palonosetron | •Oral : 0,5
mg •Parenteral : 0,25 mg IV |
1,5 mg per
hari |
30 mg/kg | Dosis tunggal
palonosetron intravena pada 30 mg / kg (947 dan 474 kali dosis manusia untuk tikusmematikan tikus dan tikus |
- |
7. | Tropisetron | •Oral BB
>25 kg : 1x sehari 5 mg •Parenteral : 5 mg injection |
5 mg/ hari | 265 mg/kg
(Rat, oral). |
LD50: 265 mg/kg
(Rat, oral). |
- |
8. | Granisetron | oral 1-2 mg | maks 2 dos
(2mg) dlm 1 hr |
2.3943
LD50, mol/kg |
LD 50 > 2000 mg /
kg (tikus, oral) |
- |
9. | Dimenhydrinate | •Dewasa
dan anak > 12 tahun 50 mg •Usia 8-12 tahun 25 mg •Usia 5-8 tahun 12,5 mg |
400 mg
sehari |
10-15 mg/kg | 62.5 mg (11.6 mg/kg) | 25-100 mg
per oral setiap 6 jam, |
10. | Pyrathiazine | 40-80 mg | - | - | - | - |
11. | Chlorpromazine | Oral: 10-25
mg Im,iv : 25- 50 mg |
800 mg/hari | 100-200
ug/Dl |
0.3-1.2 mg/dL | - |
12. | Ramosetron
Hidroklorida |
0,3 mg
sekali sehari |
0,6 mg per
hari |
- | - | - |
13. | Ondansetron | oral: 8 mg | - | - | - | 10-500 |
ng/ml | ||||||
14. | Klorpromazin
Hidroklorida |
ANAK:
500 mcg/kg bb |
•15tahun
maksimal 40mg/hari, •6-12tahun maksimal 75 mg/hari |
- | - | - |
15. | Perfenazin | 4 mg, 3
kali/hari |
24 mg/hari | - | =318mg/kg
(rat);IPR =64mg/kg (tikus) |
5.0 – 30.0
ng/mL Low-dose therapeutic range: 0.5 – 2.5 ng/mL. |
16. | Trifluoperazin | oral: 2-4
mg/hari , dosis terbagi |
6 mg/hari | - | - | - |
17. | Meclizine | 25-50 mg | - | - | - | - |
dalam dosis
terbagi |
||||||
18. | Trimethobenzamide | 300 mg
t.d.s oral ; 200 mg t.d.s inject |
- | 71 mg/kg | Oral LD50 in mice is
1600 mg/kg. |
Oral : 300
mg kasul Parenteral : 200 mg ( 2 ml ) |
19. | Compazime | 5- 10 mg
t.d.s |
- | - | =400mg/kg | - |
20. | Haloperidol | 0,5-2 mg | 30mg/hari | 3.43670
mol/kg |
LD50=165 mg/kg
(rats, oral) |
5-20 ng/ml |
21 | Olanzapine | 10 mg
sehari |
20 mg
sehari |
2.69720
mol/kg |
0.45g | 10-80
ng/ml |
22 | Metoclopramide | 10 mg/2,5
mL |
tidak boleh
melebihi 500 mcg/kg bb |
2.63320
mol/kg |
Oral, mouse LD50:
280 mg/kg. |
- |
23 | Droperidol | 0.01 –
0.015 mg/kg/dosis |
2.5 mg IM
atau slow |
2.5820LD50,
mol/kg |
LD50 20-43 mg/kg
pada tikus |
- |
IM atau IV | IV | |||||
24 | Prochlorperazine | Tablet :
5 - 10 mg 3 -4 kali sehari Kapsul : 10-15 mg |
Dosis
tunggal obat tidak boleh melebihi 10 mg. Total dosis infus tidak boleh melebihi 40 mg/hari. |
2.3496
LD50, mol/kg |
LD50=400mg/kg | - |
25 | Dipyridamole | Oral 300-
600 mg sehari 3-4 dosis terbagi sebelum makan. |
- | LD 50 =
8,4g/kg (secara oral pada tikus) |
- | - |
26 | Lorazepam | 0.05 mg/kg | 2 mg/ml | Pada tikus
oral 1850mg/ml |
- | - |
27 | Amitriptyline | - | 25 mg/hari | 350 mg/Kg | - | - |
28 | Alprazolam | 0.5-0.75 mg
sehari dalam dosis terbagi |
- | - | Oral, tikus : LD50 =
1020 mg/kg |
- |
29 | Tamsulosin | - | 0.8 mg per
hari |
- | LD50 = 650 mg/kg
(pada tikus) |
|
30 | Omeprazole | 20 mg/hari | - | 40 mg sekali sehari |
DAFTAR PUSTAKA
1. Centers for Disease Control and Prevention. December 12, 2011. Put your medicines up and away and out of sight -
2. The Center for Improving Medication Management and the National Council on Patient Information and Education. The quick scoop: medicines and your family: safely storing and disposing of medicines - Diakses: June 10, 2016.
3. U.S. Food and Drug Administration. December 24, 2013. How to dispose of unused medications –
4. World Health Organization: Information sheet: Pharmaceuticals in drinking-water –
5. Lyon, R. C., Taylor, J. S., Porter, D. A., et al. (2006)
Stability profiles of drug products extended beyond labeled expiration dates. Journal of Pharmaceutical Sciences; 95:1549-60 -
6. Harvard Medical School (2016). Drug Expiration Dates - Do They Mean Anything? –
http://de.drogen.wikia.com/wiki/LSD http://dechacare.com/OMEPRAZOLE-P561-1.html http://milissehat.web.id/?p=1215 http://nslijlab.testcatalog.org/show/PROMETH http://pionas.pom.go.id/monografi/ondansetron http://reference.medscape.com/drug/antivert-bonine-meclizine-343062 http://wildhealthh.com/id/pages/1349499
http://www.drugbank.ca http://www.drugbank.ca/drugs/DB00186 http://www.drugbank.ca/drugs/DB00321 http://www.drugbank.ca/drugs/DB00404 http://www.drugbank.ca/drugs/DB00975 http://www.drugbank.ca/drugs/DB01069
http://www.mipa-farmasi.com/2016/06/klorpromazin.html
https://aciibook.com/toxbook/trimetobenzamid-antiemetik/ https://bukusakudokter.org/2013/03/28/chlorpromazine/ https://pubchem.ncbi.nlm.nih.gov/compound/clebopride_malate https://www.drugs.com/dosage/compazine.html https://www.drugs.com/dosage/trimethobenzamide.html https://www.drugs.com/pro/metoclopramide-tablets.html https://www.farmasi-id.com
https://www.healthcare.uiowa.edu/path_handbook/handbook/test928.html www.mayomedicallaboratories.com
Sekian macam dosis dari obat antiemetik, sebenarnya masih banyak lagi obat dari antiemetik silahkan kalian cari lagi dan beri tahu saya di kolom komentar, kolom dosis yang kosong bukan berarti tidak ada melainkan kami tidak dapat menemukannya.
Terimakaih telah berkunjung, mohon maaf bila ada kesalahan.
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